Derived from this very idea and with the effort of many scientists, the revolutionary technique of optogenetics was born. In 1979, Francis Crick proposed a novel solution: use light to control neurons ( Boyden et al. However, with different classes of neurons communicating through vast, complex networks and fast electrical signals, it is essential to develop a method that can control neurons with precision to decode the function of neural circuit activity. ![]() To begin investigating these questions, scientists have been employing slow pharmacological and imprecise electrical stimulation techniques to control neural activity. For years, neuroscientists have been fixated on understanding how behavior and cognition arise from neural circuit activity.
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